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  A comparison of the surgical stress response after two different castration methods in horses: measured clinically and by the inflammatory markers WBC, SAA, fibrinogen, haptoglobin and iron
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 Ophav:
Hedlund, Danuta1, Forfatter
Jacobsen, Stine1, Vejleder
Thøfner, Martin B.1, Vejleder
Tilknytninger:
1Det Biovidenskabelige Fakultet, København, Danmark, diskurs:18              
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Indhold

Ukontrollerede emneord: Horse, inguinal castration, acute phase response, inflammatory response, SAA, fibrinogen, haptoglobin, iron
 Abstract: Reasons for performing the study: A common complication of castration is excessive swelling and edema of the scrotal area. This study investigated whether an inguinal approach with primary closure of the wound would reduce postoperative inflammation, swelling and edema compared to the classical open scrotal approach and, thereby, lead to reduced discomfort for the newly castrated horse. Objectives: To compare the surgical stress response in horses castrated by the scrotal approach with second intention healing of the wound, in comparison to horses castrated by the inguinal approach with primary closure of the wound; measured clinically and with blood-inflammatory markers. Study design: Prospective cohort study. Animals: Healthy stallions (n=18) referred to one equine clinic for castration. Methods: Blood levels of serum amyloid A (SAA), fibrinogen, haptoglobin, iron and WBC, were determined before castration and on postoperative days, 1, 2, 3 and 8, in two groups of horses; scrotal approach (n=9) and inguinal approach (n=9). Apart from the surgical procedure the horses were treated similarly in both groups. Results: Surgery time was significantly shorter in the scrotal group (mean = 14 min) than in the inguinal group (mean = 43 min) (P < 0.001). The scrotal group had fewer postoperative days (8%) with moderate/severe swelling of the scrotal area, in relation to the inguinal group (28%). There was no statistical significant difference between the two groups regarding temperature or the concentration of inflammatory markers postoperatively, although there was a tendency for the inguinal group to have higher levels of all inflammatory markers than the scrotal group. Conclusions and clinical relevance: An inguinal approach with primary wound closure did not elicit a lower inflammatory response or less swelling and edema of the scrotal area, than did the classical scrotal approach with the wounds left open for second intention healing. This study shows a tendency for the inguinal approach to elicit a higher inflammatory response and more swelling, although this is not statistically significant. Based on the results of this study, the inguinal approach cannot be recommended as a better option than the classical scrotal approach.
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Bogmærk denne post: https://diskurs.kb.dk/item/diskurs:31198:2
 Type: Speciale
Alternativ titel: En sammenligning af det kirurgiske stressrespons efter to forskellige kastrationsmetoder hos hest: målt kliniskt og ved inflammationsparametrerne WBC, SAA, fibrinogen, haptoglobin og jern
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Detaljer

Sprog: English - eng
 Datoer: 2012
 Sider: 52 pages
 Publiceringsinfo: København, Danmark : Institut for Produktionsdyr og Heste
 Indholdsfortegnelse: -
 Note: Veterinary Medicine, Veterinærmedicin
 Type: Speciale
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