Implementation of advanced echocardiographic methods in equine cardiology: tissue Doppler imaging and speckle tracking
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Madsen, Mette Flethøj1, Forfatter
Buhl, Rikke1, Vejleder
Koch, Jørgen1, Vejleder
1Det Biovidenskabelige Fakultet, København, Danmark, diskurs:18              
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 Abstract: This master’s thesis investigates the echocardiographic techniques tissue Dopplerimaging (TDI) and speckle tracking, and the possibilities of using them as tools inequine cardiology. The thesis is divided into two sections; Part I comprises thetheoretical foundation and Part II is an experimental study.Part I – Tissue Doppler imaging and speckle tracking are two recently developedechocardiographic techniques. Both have the ability to quantify regionalmyocardial function, although they rely on very different technicalities. The twomethods analyze the three-dimensional motion and deformation of themyocardium that happens with each heart beat, by assessing four parameters(velocity, displacement, strain and strain rate) along three cardiac axes (i.e. thelongitudinal, radial and circumferential).Common to the two methods is that only a very limited number of studies havebeen made on horses. Hence, the goal of this thesis was to investigate theprospects of implementing the two techniques in equine cardiology. However, theechocardiographic examination of the horse involves some restrictions due to theanatomy of this species – thus the implementation of TDI and speckle tracking inequine cardiology involves some technical challenges. Therefore, a pilot trial wasdesigned to evaluate the performance of the two techniques in the horse and theirfeasibilities for appliance in equine sports medicine.Part II – Material: The study population comprised two groups of healthy adulthorses (6 athletic and 5 non-athletic). Method: Two study protocols wereperformed. Protocol 1 investigated the method agreement of the two techniquesand the correlation on TDI measures taken from different examinations anddifferent offline analyses, respectively. Protocol 2 compared the measures of thetwo groups of horses to determine if the two techniques would be able todistinguish between athletic and non-athletic horses. Results: In general, theresults showed a high degree of dispersion, presumably due to some specific errorsin the conduction of the study. The level of agreement between TDI and speckletracking on the size of the measures varied with the individual parameters. Thecorrelation of TDI measures from different examinations was diverse, while themeasures obtained from different offline analyses all showed a strong positivecorrelation. Very few significant differences between the athletic and non-athletichorses were found. However, evaluation of the sample sizes revealed that thesewere too small to make any valid conclusions. Conclusion: Despite the restrictednumber of solid conclusions in the study, this thesis has provided both knowledgeand tools that can be of value in the conduction of future studies.
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Sprog: English - eng
 Datoer: 2008
 Sider: 128 pages
 Publiceringsinfo: København, Danmark : Institut for Produktionsdyr og Heste
 Indholdsfortegnelse: -
 Note: Veterinary Medicine, Veterinærmedicin
 Type: Speciale
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