Holter monitoring in cats: heart rate variability and arrhythmia analysis in healthy cats and cats with hypertrophic cardiomyopathy
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Christensen, Christina1, Forfatter
Koch, Jørgen1, Vejleder
Granström, Sara1, Vejleder
1Det Biovidenskabelige Fakultet, København, Danmark, diskurs:18              
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 Abstract: Objectives: This study aimed to establish a protocol for Holter monitoring in feline patients, and by doing so compare healthy cats and cats with hypertrophic cardiomyopathy (HCM) in relation to arrhythmia frequency and heart rate variability (HRV).Background: Holter monitoring has become a valuable diagnostic tool in veterinary medicine, although it has not yet been widely used in feline studies. Cats with HCM tend to have an increase in arrhythmia frequency, and the same has been shown to be evident in human HCM patients, where also a decrease in HRV has been observed. Animals: Seven cats with HCM and six healthy cats.Methods: All cats were given echocardiographic examinations to verify their HCM status. The cats underwent 24-hour Holter monitoring, which in all but two cats was carried out in their home environment. The recordings were analysed focusing on heart rate (HR), types and frequency of arrhythmias and pre-selected HRV measurements. The results were compared between the two groups.Results: The cats tolerated the application and the wearing of the Holter recorder well, and high quality recordings were obtained. HR recorded during echocardiography was found to be significantly higher (p <0.002), when compared to mean HR obtained during Holter monitoring. A higher number of cats with HCM tended to experience bradycardia and sinus pauses (p <0.04), than the healthy cats. The HCM group also tended to have a higher number of ventricular premature complexes (VPCs) (p <0.04), when the first hour of recording was removed. Significant correlation was found between several HRV measurements analysed by time and frequency domain analysis.Conclusions: Holter monitoring can easily be used on feline patients, although some adjustment to the settings of the analysing program and thorough manual editing is necessary. Cats with HCM seem to experience a higher number of VPCs compared to healthy cats, which is similar to findings in previous studies. Looking at findings in human reports, HRV constitutes an interesting tool in the prognostic evaluation in cats diagnosed with HCM.
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 Type: Speciale
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Sprog: English - eng
 Datoer: 2008
 Sider: 88 pages
 Publiceringsinfo: København, Danmark : Institut for Mindre Husdyrs Sygdomme
 Indholdsfortegnelse: -
 Note: Veterinary Medicine, Veterinærmedicin
 Type: Speciale
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